PCR and DNA Analysis
Combination of cell cultivation and genetic analysis is useful in many biological applications, for example, to improve sensitivity for mutation frequency analysis of heterogeneous tumor samples. By performing all steps in the Picovitro plate the proliferation and cell morphology of every single cell or clone can be linked to its genetic information. In addition, expanded cells (i.e. the clone) give more genetic material for analysis, as compared to single cell PCR.